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Anaphylaxis in Infants & Children: Responding to Severe Allergic Reactions

Anaphylaxis in Infants & Children Anaphylaxis in Infants & Children

By: Julie Wang, MD, FAAP, FAAAAI

Anaphylaxis is a rapid and severe allergic reaction. It is also a life-threatening emergency.

A rising number of children being treated in emergency departments for anaphylaxis in recent years. At any age, anaphylaxis can be deadly without immediate medical help.

Allergic reactions are unpredictable in terms of when they happen, what types of symptoms develop, and the severity of those symptoms. They can happen to children at any age, including infants. Being prepared and knowing the signs of an allergic reaction can save a child's life.

How do I know if my child is having an allergic reaction?

Anaphylaxis includes a wide range of symptoms that can start quickly—within minutes or several hours after exposure to an allergy trigger.

Be aware of any of the following symptoms, especially if they appear suddenly:

  • shortness of breath, wheezing, coughing or tightness in chest

  • trouble breathing or swallowing

  • skin changes like rash, redness or hives and/or pale or bluish color

  • swelling of the lips or tongue

  • sneezing, stuffy nose, runny nose

  • tight throat, difficulty swallowing, hoarseness

  • weak pulse, symptoms of shock

  • vomiting, diarrhea (if severe or combined with other symptoms)

  • dizziness or fainting

  • feeling of "doom," confusion, drowsiness or agitation

Infants may also experience other symptoms such as:

  • irritability, fussiness, or inconsolable crying  

  • sudden drooling 

  • unusual sleepiness 

Epinephrine is the recommended emergency treatment for symptoms of anaphylaxis.

Epinephrine helps quickly reverse the life-threatening symptoms of anaphylaxis.

If it is available, epinephrine should be given immediately to anyone experiencing symptoms of anaphylaxis, followed by a call to 911 and a trip to the emergency department.

Epinephrine auto-injectors & nasal sprays for kids

Epinephrine comes in auto-injector syringes and nasal sprays to treat anaphylaxis.

  • Auto-injectors: For auto-injectors (sometimes called "EpiPens"), the best place to inject it is in the muscles of the outer part of the thigh.

  • Nasal sprays: Epinephrine nasal sprays to treat anaphylaxis are now approved for children weighing 66 pounds or more.

Who should carry epinephrine?

Epinephrine should be prescribed for anyone who has ever had an anaphylactic attack and for infants and children at high risk for anaphylaxis. Because a second dose may be needed if symptoms don't ease quickly, children at risk for anaphylaxis should carry at least two doses of epinephrine with them at all times.

Children who are old enough can be taught how to give themselves epinephrine, if needed. Epinephrine should be readily available in school or child care settings and trained staff should be available to act quickly in case of a reaction. Keep in mind, schools may require detailed instructions from your child's doctor about how and when to use it. See When When Your Child Needs Medication at School: Tips for Parents.

What to do after giving an infant or child epinephrine:

  • Note what time the epinephrine was given and call 911. Ask for an ambulance with epinephrine. Tell rescue squad when epinephrine was last given when they arrive.

  • Stay with child and give a second dose of epinephrine if: symptoms get worse, continue, or do not get better in 5 minutes.

  • Keep child lying on his or her back. If the child vomits or has trouble breathing, keep child lying on his or her side.

  • Give other prescription medicine (such as the child's inhaler/bronchodilator or an antihistamine prescribed by the doctor), but never use other medicine in place of epinephrine.

Lots of things can cause a severe allergic reaction

Common Allergens that Can Trigger Anaphylaxis

Foods

  • Peanuts are one of the most common U.S. food allergies. The American Academy of Pediatrics advises parents to introduce peanut-containing foods after their baby has tried low allergy risk foods as an allergen prevention strategy for high-risk infants"

  • Milk

  • Eggs

  • Tree nuts such as walnuts, pistachios, pecans and cashews

  • Shellfish (such as shrimp, lobster)

  • Fish such as tuna, salmon, cod (although, like with peanuts, there is some evidence that consuming fish early in life may help prevent allergic diseases such as asthma and eczema).

Insect stings

  • Bees

  • Wasps

  • Hornets

  • Yellow jackets

  • Fire ants

Medicines

  • Antibiotics and antiseizure medicines are some of the more common medicines that cause anaphylaxis. However, any medicine, even aspirin and other non­steroidal anti-inflammatory drugs, have the potential to cause severe reactions.

Other

  • In rare cases, anaphylaxis may be related to a certain food followed by exercise.


Be prepared: have an allergy and anaphylaxis emergency care plan

Anyone caring for an infant or child with a life-threatening allergy must be able to recognize anaphylaxis and know when and how to give the lifesaving treatment (epinephrine).

If your child is at high risk for allergies, or has had a previous severe allergy reaction, the American Academy of Pediatrics recommends you have an Allergy and Anaphylaxis Emergency Plan. Your pediatrician can help you and your family use this plan with anyone who cares for your child. It's also clearly written and easy to understand. See for yourself!

More information

About Dr. Wang

Dr. Julie Wang, MD, FAAPJulie Wang, MD, FAAP, FAAAAI, is a Professor of Pediatrics in the Division of Allergy and Immunology at the Icahn School of Medicine at Mount Sinai in New York and a clinician and clinical researcher in the Jaffe Food Allergy Institute. Dr. Wang is past Chair of the American Academy of Pediatrics Section on Allergy & Immunology.


Last Updated
8/12/2024
Source
American Academy of Pediatrics Section on Allergy and Immunology (Copyright © 2024)
The information contained on this Web site should not be used as a substitute for the medical care and advice of your pediatrician. There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances.
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