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Where We Stand: Folic Acid During Pregnancy

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In an effort to reduce the prevalence of spina bifida, the American Academy of Pediatrics (AAP) endorses the recommendation of the U.S. Public Health Service that everyone capable of becoming pregnant consume 400 micrograms (mcg) per day of folic acid, a B vitamin.

Help prevent neural tube defects

Folic acid helps to prevent neural tube defects (NTD), which include spina bifida. Although some foods are fortified with folic acid, it is not possible to meet the 400 mcg goal through a typical diet. That is why an AAP policy statement recommends a daily multivitamin tablet that contains folic acid in the recommended dose. Studies show that if all women of childbearing age met these dietary requirements, 50% or more of NTDs could be prevented.

Talk with your doctor about folic acid

Anyone who is at high risk for an NTD-affected pregnancy (for example because of a previous NTD-affected pregnancy, having diabetes mellitus, or taking antiseizure medications) are advised to discuss their risk with their doctor. This includes possible treatments with very high doses of folic acid (4,000 mcg per day), beginning one month before becoming pregnant and continuing throughout the first trimester.

However, the AAP advises against trying to achieve this very high dose of folic acid by taking multivitamin supplements, however. That's because there is a risk of getting too much of other vitamins this way. Instead, be sure to follow the advice of your doctor about high-dose folic acid treatment.

More information

Last Updated
2/28/2025
Source
Adapted from Caring for Your Baby and Young Child: Birth to Age Five 8th edition (Copyright © 2024 American Academy of Pediatrics)
The information contained on this Web site should not be used as a substitute for the medical care and advice of your pediatrician. There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances.
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